Depro-Provera is a shot of progestin which must be given once every three months. Like Norplant and the Pill, Depro-Provera prevents ovulation. It also causes changes in the cervical mucus which prevent sperm from entering the uterus.
The first shot of Depro-Provera must be given within five days of the beginning of a period unless the woman has been using the Pill or an IUD. Depro-Provera begins to give protection against pregnancy within 24 hours of the first shot. The medicine slowly wears off over time, and one cannot count on being protected from pregnancy after the twelve week mark.
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